When investigating and optimising drug delivery via inhalores the process can be subdivided into
the following steps:
- 1- Atomization
- 2- Particle transport in the inhaler and spacer
- 3- Transport in upper part of respiratory system
- 4- Transport in deep lung
Steps 2 and 3 can be readily investigated using standard CFD techniques. Steps 1 and 4 require special
models to describe the atomization and drug delivery in the lung.
The second figure shows an Oro-pharyngeal CT scan and the calculated flow conditions during breath intake.